E-cigarettes increase the risk of heart disease from the first use

Damage to blood vessels from e-cigarettes?

When using e-cigarettes, vapors are produced which impair the functioning of the blood vessels in healthy people. These negative effects could already be observed when people started using e-cigarettes for the first time.

A recent study by the University of Pennsylvania found that vaporizing liquids in e-cigarettes affects blood vessel function. The results of the study were published in the English-language journal "Radiology".

Can E-Cigarettes Cause Cardiovascular Disease?

Changes in the cardiovascular function after the use of e-cigarettes were even observed when using liquids without nicotine. With the help of MRI examinations, changes in the blood flow in the femoral artery in the leg were found after just one use of e-cigarettes, the researchers report. After a few minutes everything will normalize again. However, if people use e-cigarettes regularly, there is a chance that the effects will not normalize as quickly. Evaporation triggers processes that initiate the development of cardiovascular diseases, including arteriosclerosis. The development then probably takes several years, explains the research group.

How do e-cigarettes affect the heart, blood vessels, lungs and brain?

The current study is the latest addition to an increasing number of research projects to measure the effects of e-cigarettes on the heart, blood vessels, lungs and brain. Research on this topic is still at an early stage and often only takes place in the laboratory or is carried out on animals. For example, a study in May indicated that e-cigarette flavors had toxic effects on some type of cardiovascular cell in the laboratory, including poor cell survival and signs of increased inflammation.

Many long-term effects are completely unknown

The use of e-cigarettes continues to grow and the data demonstrating potential harm is increasing. In addition to nicotine damage, the additives are a potential source of damage to vascular health, which particularly affects young people, the researchers explain. There is an idea that vaping poses a lower health risk than smoking cigarettes. The research group said that little is known about the potential toxicology of flavors, particles, heavy metals and other ingredients used in e-cigarettes. It is not yet clear what it means for human lungs to inhale and exhale propylene glycol and glycerin repeatedly in aerosol form, the team adds. Many substances used by the aroma industry are safe if they are absorbed through the intestine, but so far it is not known what effects they can have on the lungs over a long period of time, the researchers report. (as)

Author and source information

This text corresponds to the specifications of the medical literature, medical guidelines and current studies and has been checked by medical doctors.


  • Alessandra Caporale, Michael C. Langham, Wensheng Guo, Alyssa Johncola, Shampa Chatterjee, Felix W. Wehrli: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function Detected at Quantitative MRI, in Radiology (query: 21.08.2019), Radiology

Video: One e-cigarette with nicotine leads to adrenaline changes in nonsmokers hearts. UCLA Health (January 2022).